Detalhe da pesquisa
1.
Inhibition of ASGR1 decreases lipid levels by promoting cholesterol excretion.
Nature
; 608(7922): 413-420, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35922515
2.
Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis.
Nature
; 588(7838): 479-484, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33177714
3.
New Loss-of-Function Mutations in PCSK9 Reduce Plasma LDL Cholesterol.
Arterioscler Thromb Vasc Biol
; 43(7): 1219-1233, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37165876
4.
Disruption of the ERLIN-TM6SF2-APOB complex destabilizes APOB and contributes to non-alcoholic fatty liver disease.
PLoS Genet
; 16(8): e1008955, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32776921
5.
SUMOylation of the ubiquitin ligase IDOL decreases LDL receptor levels and is reversed by SENP1.
J Biol Chem
; 296: 100032, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33154164
6.
POST1/C12ORF49 regulates the SREBP pathway by promoting site-1 protease maturation.
Protein Cell
; 12(4): 279-296, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32666500
7.
Gpnmb secreted from liver promotes lipogenesis in white adipose tissue and aggravates obesity and insulin resistance.
Nat Metab
; 1(5): 570-583, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32694855
8.
The GARP Complex Is Involved in Intracellular Cholesterol Transport via Targeting NPC2 to Lysosomes.
Cell Rep
; 19(13): 2823-2835, 2017 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28658628